منابع مشابه
The Italian “iort Project”
The “Intra Operative Radiation Therapy” (IORT) represents the latest technological frontier in radiotherapy. The technique utilizes accelerated electrons, as from a tailored designed EB-machine, to destroy rapidly spreading malignant cancer cells and it is appraised to allow a 15% general increase of cancer patients survival. The Italian “IORT Project”, funded by the Italian Ministry of Researc...
متن کاملBiology of high single doses of IORT: RBE, 5 R’s, and other biological aspects
Intraoperative radiotherapy differs from conventional, fractionated radiotherapy in several aspects that may influence its biological effect. The radiation quality influences the relative biologic effectiveness (RBE), and the role of the five R's of radiotherapy (reassortment, repair, reoxygenation, repopulation, radiosensitivity) is different. Furthermore, putative special biological effects a...
متن کاملIntraoperative Radiation Therapy (IORT) | Clinical Review Criteria
NOTICE: Kaiser Foundation Health Plan of Washington and Kaiser Foundation Health Plan of Washington Options, Inc., provide these Clinical Review Criteria for internal use by their members and health care providers. The Clinical Review Criteria only apply to Kaiser Foundation Health Plan of Washington and Kaiser Foundation Health Plan of Washington Options, Inc. Use of the Clinical Review Criter...
متن کاملIs IORT ready for roll-out?
Two large randomised controlled trials of intraoperative radiotherapy (IORT) in breast-conserving surgery (TARGIT-A and ELIOT) have been published 14 years after their launch. Neither the TARGIT-A trial nor the ELIOT trial results have changed the current clinical practice for the use of IORT. The in-breast local recurrence rate (LRR) after IORT met the pre-specified non-inferiority margins in ...
متن کاملPresent state and issues in IORT Physics
Literature was reviewed to assess the physical aspects governing the present and emerging technologies used in intraoperative radiation therapy (IORT). Three major technologies were identified: treatment with electrons, treatment with external generators of kV X-rays and electronic brachytherapy. Although also used in IORT, literature on brachytherapy with radioactive sources is not systematica...
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ژورنال
عنوان ژورنال: Journal of Thoracic Oncology
سال: 2018
ISSN: 1556-0864
DOI: 10.1016/j.jtho.2018.08.144